Some determinats of developing pediatric renal dysfunction

ABSTRACT

One hundred and ten children [72 males and 38 females aged from 7 to13 years] having a minimally elevated plasma creatinine level of1.4-1.7 mg/dl were enrolled in the present study. Trends in crude relative risk [RR] of renal dysfunction across the plasma lipid categories were calculated using Poisson regression. This relative risk was adjusted for the body mass index [BMI], defining over weight as BMI >90th centile. Higher baseline plasma levels of lipids [triglycerides, HDL cholesterol and LDL cholesterol] had a statistically significant higher risk of future renal dysfunction. The same association was maintained after adjustment for the BMI, with the exception that the association between LDL cholesterol and creatinine clearance was insignificant