Adult acute nonlymphocytic leukemia in Saudi Arabia: experience at King Khalid University Hospital in Riyadh

ABSTRACT

Twenty-two adult patients with acute nonlymphocytic leukemia [ANLL]] were analyzed. There were 15 males [68%] and 7 females [32%]. Their median age was 42 years. Thirty-six percent had acute myelomonocytic leukemia [M4], and 46% had acute monocytic leykemia [M5], according to the French-American-British classification. Of 17 patients who received intensive combination chemptherapy, 47% achieved complete remission. Of the subgroup of 14 new and the patients previously mutreated patients, the complete remissian rate was 57%. The rest of died of septic complications. We report an increased ratio of M4 and M5 in ANLL in Saudi Arabia and an increased rate of severe septic and fungal complications