Doppler study of umbilical and uterine blood flow, biophysical profile scoring, placental grading and maternal glycosylated hemoglobin in diabetic pregnancy

ABSTRACT

Biophysical profile scoring, placental grading and Doppler velocity waveforms from both the uterine and umbilical arteries were recorded in 50 pregnant women few days before termination of their pregnancies among whom 20 were normal control group and 30 were diabetics who were further subdivided by the level of their blood glycohemoglobin into 15 controlled diabetics and 15 uncontrolled diabetics. The results were studied, compared and correlated with the fetal outcome. A/B ratio from the umbilical artery was found to be a good tool for prediction of fetal condition in utero and neonatal outcome. It was strongly correlated with the diabetic control measured by the third trimester glycohemoglobin. It was found more sensitive than the uterine A/A ratio which was found unrelated to the fetal outcome in diabetic pregnancy