Premedication with midazolam [dormicum] compared with promethazine, droperidol and placebo in relieving anxiety using Beck's anxiety inveutory

ABSTRACT

In a randomized double blind study, midazolam [dormicum[R]] [7.5 mg] was compared with promethazine [phenergan [R]] [25 mg], droperidol [2.5 mg] and placebo as premedication for 98 pre selected patients undergoing surgery. The anxiolytic effect of the above drugs was monitored by beck's anxiety inventory. 83.3% of patients who received midazolam had a decrease in their anxiety state compared to 55.6% for promethazine, 12% for droperidol and 25% for placebo. The study clearly proved that midazolam is a better anxiolytic drug compared to droperidol and promethazine