Survival of living-related kidney graft recipients in the era of modern immunosuppressive treatment
Annals of Saudi Medicine. 2011; 31 (3): 279-283
in English
| IMEMR
| ID: emr-122618
ABSTRACT
Currently, there is no consensus about immunosuppressive therapy following kidney transplantation. Acute rejection rates and allograft survival rates are the clinical outcomes traditionally used to compare the efficacy of various immunosuppressive regimens. Therefore, we conducted this study to evaluate whether patient survival rates improved in the era of modern immunosuppressive treatment during living-related kidney transplantation. Retrospective cohort study in a university-based tertiary internal medicine teaching hospital performed between 1999 and 2009 and patients followed up to 7 years. Survival rates were assessed in 38 patients receiving basiliximab and mycophenolate mofetil [regimen A] and 32 patients receiving antithymocyte globulin and azathioprine [regimen B]. The rest of the regimen [cyclosporine A and steroids] remained the same. A secondary end point was acute rejection episode. Seven-year survival rates were 100% and 72% [P=.001] and 7-year acute rejection-free survival rates were 82% and 53% [P=.03], in groups A and B, respectively. Long-term survival after living-related kidney transplantation has improved in the era of modern immunosuppressive treatment
Search on Google
Index:
IMEMR (Eastern Mediterranean)
Main subject:
Survival Rate
/
Retrospective Studies
/
Cohort Studies
/
Kidney Transplantation
/
Drug Therapy, Combination
/
Graft Survival
/
Immunosuppressive Agents
Type of study:
Incidence study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Ann. Saudi Med.
Year:
2011
Similar
MEDLINE
...
LILACS
LIS