[Diabetic ketoacidosis in a patient with acromegaly, a case report]
Journal of Mazandaran University of Medical Sciences. 2007; 17 (57): 99-102
in Persian
| IMEMR
| ID: emr-123189
ABSTRACT
Although impaired glucose tolerance affects 36% and overt diabetes mellitus can be seen in 30% of cases with acromegaly, diabetic ketoacidosis is rarely reported in patients with this disease. We present an unusual complication of acromegaly a 22 year old woman with amenorrhea [6 month age] and blurred vision of left eye [4 month ago] referred to Ghaem neurology clinic in Mashhad. With a growth hormone [GH] level of = 100 ng/ml, Insulin like growth Factor-1 [IGF-1] =1560 ng/ ml and pituitary macro adenoma in magnetic resonance imaging [MRI], she was candidated for surgery. A few hours before surgery she had dyspnea, loss of consciousness, fever and with blood sugar [BS] =500 mg/ml, Hco3 = 2.4, PH=7.06 and keton in urine. Diabetic ketoacidosis was diagnosed. The patient was treated with high dose of insulin [500 IU/day] and hydration. After octerotide administration the need for insulin decreased and after pituitary adenectomy, there was no need for insulin therapy and the patient was discharged on metformin [one tablet per day]
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Pituitary Neoplasms
/
Acromegaly
/
Magnetic Resonance Imaging
/
Diabetes Complications
/
Diabetes Mellitus
/
Insulin
/
Metformin
Type of study:
Case report
Limits:
Female
/
Humans
Language:
Persian
Journal:
J. Mazandaran Univ. Med. Sci.
Year:
2007
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