Low serum zinc and higher risk of CA prostate in local population study

ABSTRACT

Study was designed to evaluate the Serum status of Zinc in CA Prostate patients and then match to PSA levels to obtain any significant correlation of Serum Zinc values the risk of CA prostate. Study was conducted at the Biochemistry Department of B.M.S.I, JMPC. Diagnosed CA Prostate cases were selected with the collaboration of Urology and Radiotherapy Department, J.P.M.C, Karachi since June 2006 to July 2007. Total thirty five [35] diagnosed CA Prostate patients and thirty five controls were participated in the study. Zinc and PSA were measured in the blood samples of prostate patients. Significant low zinc blood levels [p<0.05] and significantly high levels of PSA [p<0.05] in the CA Prostate patients as compared to control were found. Serum zinc was estimated in prostate cancer patients, we found significantly decreased levels of zinc [p<0.005] in cancer patients when compared to control group