Left ventricular function in cholestatic jaundice

ABSTRACT

Left ventricular functions were studied in 10 normal healthy controls and 57 patients with cholestatic jaundice of more than 6-week duration. The QS2 interval was insignificantly increased, the LVET was significantly shortened and PEP was significantly prolonged. These findings pointed to the impaired left ventricular performance in cholestatic jaundice. Direct myocardial depression by bile salts or decreased sympathetic drive were incriminated for the impaired left ventricular function