Role of low molecular weight heparin

ABSTRACT

To evaluate the effectiveness of LMWH prophylaxis for DVT in high risk patients after general surgery. Randomized controlled study. Surgical Unit-IV, District Head Quarters Hospital, Faisalabad. From March 2009 to August 2009. Sixty patients in the LMWH group were given perioperative enoxaparin [Clexane] as prophylaxis while compression stockings were used in another control group comprised of 60 patients. At 5th postoperative day, Doppler study was performed to detect DVT in both groups. Categorical data were analyzed for significance using Chi square test through SPSS. There were significant difference in age factor, history of DVT, Medical factor, surgical trauma factor and interpretation on the basis of points. However, there is non significant difference between LMWH group and control group for chemoprophylasis. LMWH administration is effective for the prevention of venous thromboembolism in high risk patients and its practice should be the standard of care in the practice of surgery