Leucocytic margination in typhoid and hepatosplenic bilharziasis

ABSTRACT

Adrenaline injection induced a significant blood cellular changes, which were more at phase I than at phase II except a reverse pattern occurs to platelets, phase II of adrenaline response is not to stimulation of pituitary adrenal axis, the total leucocytic counts were positively correlated with neutrophils and lymphocytes. In bilharzial cases, the maximum adrenaline induced increase of the formed blood elements was larger than in normal persons, negative correlation between grades of splenomegaly and base line level of all formed blood cells, positive correlation between grades of splenomegaly and the maximum adrenalin test can be used a diagnostic of cellular sequenstration in grades II and III bilharzial splenomegaly. Marginal bool of noutrophils is increased and positively correlated with the grades splenomegly and the maximum increase of lymphocytes after adrenaline test was larger than that of neutrophils. A suggestion for lymphocytes margination and was positively correlated with the grade of splenomegaly. In enterica, neutrpenia is due to increase of their marginal pool, relative lymphocytosis may b due to decrease of their margination. The maximum increase of lymphocytes after adrenaline injection was lower than of neutrophils