Neutrqphils phagocytic power in chronic asthmatic bronchitis and pulmonary tuberculosis

ABSTRACT

This work comprised 16 and 14 tuberculous patients in addition to 16 healthy control subjects. All cases were submitted to full history taking, thorugh clinical examination, x-ray chest, laboratory investigations including urine analysis, stool analysis, blood picture, E.S.R., serum creatinine and post prandial .blood sugar. Sputum smear with Ziehl Neelsens and sputum culture and sensitivty test. Estimation of serum IgA, G, Mi and C[3], and determination of the phagocytic power of neutrophils. The asthmatic and control groups were subjected to pulmonary function tests. The results revealed mild anaemia with normal leucocytic count in both groups. The phagocytic power of neutrophils was markedly depressed in all patients which is mainly due to cellular defect, rather than humoral as there is normal serum IgA and C[3] and elevated IgM and IgG. The only specification in tuberculous group is elevation of C[3] with no difference in phagocytic power among sputum positive and negative subgroups