Experimental evaluation of some oral anti-schistosomal drugs

ABSTRACT

The oral antischistosomal drugs [vansil and biltricid] were investigated experimentally on albino rats with paracetamol induced hepato-renal toxicity. A biochemical and histopathological studies were done on such animals and were compared with normal and paracetamol treated ones. It is found that vansil is less toxic than biltricid as the last one causes more hepatorenal affection together with pulmonary congestion which is lacking in the vansil treated ones. Both drugs produce no testicular changes