Histological evaluation of the pulp of primary teeth after pulpotomy with formocresol and SUAB2

ABSTRACT

Formocresol is a popular pulpotomy medicament in primary dentition. Because of its systemic and local side effects, it may be essential to use another material instead of formocresol. The purpose of this study was to assess the pulpal response after pulpotomy histologically with two different agents; namely, formocresol and SUAB2. In this randomized clinical trial study, 14 teeth of seven children that should had been extracted because of orthodontic treatment were selected. These teeth were randomly divided into two formocresol and SUAB2 [Shahed University Anti Bleeding 2] groups. Seven teeth were pulpotomized with formocresol and seven teeth with SUAB2. These teeth were extracted after 2 months and the pulpal response was evaluated. Finally, the data were analyzed with exact fisher and Mann-Whitney tests. In the formocresol group, severe inflammation was seen in four teeth, mild inflammation in three teeth, abscess in four teeth, necrosis in two teeth, fibrosis in three teeth and internal resorption in four teeth. In the SUAB2 group, severe inflammation was not seen. Moderate and mild inflammation was seen in four teeth, abscess in two teeth, necrosis in two teeth, fibrosis in three teeth and internal resorption in four teeth. Mann-Whitney test revealed that inflammation is significantly less in the SUAB2 group compared with the formocresol group [p<0/05]. Based on the results of this study, SUAB2 may be used in primary teeth pulpotomy