Vitamin D toxicity in adults: a case series from an area with endemic hypovitaminosis D
Oman Medical Journal. 2011; 26 (3): 201-204
in English
| IMEMR
| ID: emr-125055
ABSTRACT
Vitamin D deficiency state is endemic to the Kashmir valley of the Indian subcontinent. Physicians often treat patients with high doses of vitamin D for various ailments and on occasion the prescribed doses far exceed the requirements of the patients. Ten cases of hypercalcemia due to vitamin D intoxication are presented with features of vomiting, polyuria, polydipsia, encephalopathy and renal dysfunction. All the patients had demonstrable hypercalcemia and vitamin D levels were high in nine of the 10 cases. The patients had received high doses of vitamin D and no other cause of hypercalcemia was identified. Treatment of hypercalcemia resulted in clinical recovery in nine cases. We conclude that hypervitaminosis D must be considered in the differential diagnosis of patients with hypercalcemia in endemically vitamin D deficient areas. A careful history and appropriate biochemical investigation will unravel the diagnosis in most of the cases
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Avitaminosis
/
Vitamins
/
Diagnosis, Differential
/
Emergencies
/
Drug Overdose
/
Hypercalcemia
Type of study:
Case report
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Oman Med. J.
Year:
2011
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