Cardiac enzymes activities and troponin-1 level in rabbit invested with intestinal and hepatic coccidiosis

ABSTRACT

This study was performed to elucidate the effect of both intestinal and hepatic coccidiosis on cardiac enzymes, GST, Catalase activities as well as troponine 1 level in rabbits. Furthermore, the study was extended to investigate the activities of the previous parameters after treatment of invested rabbits with coccidiosis. In this study, thirty six male rabbits were divided into 6 groups. Group 1 is a healthy control group. Groups 2, 3, 4, 5 and 6 were design as invested with intestinal type of coccidiosis, infected with hepatic type of coccidiosis, control treated with sulpha drug, infected with intestinal coccidiosis and treated with sulpha drug, infected with hepatic coccidiosis and treated with sulpha drug group, respectively. cardiac enzymes as AST, CPK, CPK-MB and LDH increased than the normal level during coccidial infection, either hepatic or intestinal type but it more pronounced in hepatic one after 7 and 14 days of infection. Also, troponine 1 level was increased significantly in the groups infected with intestinal and hepatic coccidiosis than the control group at 7 and 14 days from infection, whereas GST, Catalase activities decreased significantly in groups infected with either intestinal and hepatic coccidiosis than control one. Pretreatment with sulpha drugs improve the biochemical parameters changed by coccidial infections