Your browser doesn't support javascript.
loading
Synthesis of novel 1,4-disubstituted piperazines as potential antihypertensive agents
Egyptian Journal of Pharmaceutical Sciences. 1989; 30 (1-4): 419-27
in English | IMEMR | ID: emr-12798
ABSTRACT
Two series of 1-arylpiperazines linked to nicotinic acid moiety were prepared as potential antihypertensive agents. The first series [compounds II] was prepared via the Mannich reaction of N-nicotinoyl with 4-amino-benzoic acid to give N-nicotinoyl-4-aminobenzoic acid. The latter was treated with thionyl chloride to give the corresponding acid chloride which was reacted with 1-arylpiperazines to give IV. Preliminary screening of the synthesized compounds was performed for their antihypertensive activity
Subject(s)
Search on Google
Index: IMEMR (Eastern Mediterranean) Main subject: Antihypertensive Agents Language: English Journal: Egypt. J. Pharm. Sci. Year: 1989

Similar

MEDLINE

...
LILACS

LIS

Search on Google
Index: IMEMR (Eastern Mediterranean) Main subject: Antihypertensive Agents Language: English Journal: Egypt. J. Pharm. Sci. Year: 1989