[Succinylcholine-induced fasciculation prevention, with lidocaine]

ABSTRACT

Succinylcholine is a depolarizing muscular relaxant with rapid onset and short-acting effect. It is of considerable usage in emergency conditions and short - term surgeries; but has several side effects, a great deal of which will be reduced by prevention of fasciculation. This clinical - trial stady was done in the year 2006 In Ear, Nose, Throat department of Imam Reza Hospital.40 patients with ASA ? and ENT operations categorized randomly into two similar groups. Control group recieved sufentanyl 0.2 mg/kg, propofol 2.5 micro g/kg and succinylcholine 1.5 mg/kg. In case group lidocaine 1mg/kg and after 1 min succinycholine was administered. Incidence and severity of fasciculation and quality of intubation were evaluated. Data was analyzed by descriptive statistics, T - test, X - square, valis, and X[2]. Demographic parameters were not different significantly according X[2] test. There was significant difference regarding the incidence of fasciculation but there was no significant difference with respect to the intensity of fasciculation and quality of intubation. This study showed that lidocaine 1mg/kg before induction decreases succinylcholine-induced fasciculation