Cataract associated with high-dose hematopoietic colony stimulating factor, case report and literature review
SPJ-Saudi Pharmaceutical Journal. 2010; 18 (2): 107-110
in English
| IMEMR
| ID: emr-129309
ABSTRACT
Granulocyte-colony stimulating factor [G-CSF] is a lineage-restricted hematopoietic growth factor. It induces proliferation and maturation of neutrophilic precursors and progenitors and activates neutrophil functions. It is used to ameliorate or prevent profound neutropenia and its consequences. G-CSF therapy in neutropenic disorders increases neutrophil count and improves infectious complications. However, it is not without side effects. Here, we discuss the case of a 2 years old patient with Kostmann's disease who developed cataracts following high-dose G-CSF therapy. We also review the relevant literature on G-CSF-related complications
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Hematopoietic Stem Cells
/
Review Literature as Topic
Type of study:
Case report
Limits:
Humans
/
Male
Language:
English
Journal:
Saudi Pharm. J.
Year:
2010
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