[Dexamethasone plus metoclopramide for prevention of postoperative nausea and vomiting in patient undergoing adenotonsilectomy -a comparison]

ABSTRACT

Adenstonsilectomy is the most prevalent procedure in Earand nose and throat specialty, and unfortunately the main reason for delaying discharging such patients is nausea and vomiting. Meanwhile, the most prevalent side effect of this surgery is recovery from anesthesia. Using medicines with minimum complication and price which can be effective in controlling this problem and reducing side effects of patient's discharge and relevant problems, is a good option. In this study, 60 persons were candidates for Adenstonsilectomy, which have been introduced to operation room of Loghman Hospital. They have studied for a period of 6 months. These patients were divided in 2 groups each with 3 cases. In one group Dexamethasone and Metoclopramide was used and in second one Ondansetrone with sterile water at the same dosage. Immediately they received Induction, and stomach wre evacuated by NG tube. For preserving the anesthesia they received propofol 150-200 micro g/kg with 50% [O2 + N2O], then they have been supervised between 0-3, 3-12, 12-24 hours after surgery for nausea and vomiting in recovery room and at E.N.T. Ward. No statistically significant difference in nausea and vomiting had been found in these two studied goups between 0-3, 3-12, and 12-24 hours after surgery. Our study indicated that the compound Dexamethasoen and metoclopramide can be effective, the same as ondanstron, in controlling nausea and vomiting after surgery of Adenstonsilectomy during different hours, and there was no meaningful difference between these two drugs with Ondansetrone, in controlling nausea and vomiting after surgery, and in our study; Ondansetrone has no preference in using Dexamethasone and Metoclopramide simultaneously