[ incidence of hypotension, nausea and vomiting after spinal anesthesia for elective caesarean section: a comparison between bupivacaine 0.5% and lidocaine 5%]

ABSTRACT

Hypotension and nausea are common side effects during spinal anesthesia. This study compared the incidence of hypotension and nausea-vomiting induced by bupivacaine and lidocaine in parturients undergoing caesarean section under spinal anaesthesia. In this clinical trial, 120 parturients undergoing caesarean section were randomly allocated into two groups. 60 patients received subarachnoid lidocaine 5% [75-100 mg] and the other group of patients received bupivacaine 0.5% [12-15 mg]. If systolic blood pressure decreased to 80 mm Hg or less than 70% of the pre-anesthesia value, 5mg ephedrine was injected. We evaluated Blood pressure each 3 minutes up to 15 min and every 5 min thereafter till the end of the recovery stay. There was no statistically significant difference in the incidence of nausea -vomiting between the two groups after spinal anesthesia. On the other hand, there was significant difference in systolic blood pressure 12 minutes after the procedure and also a significant difference was noted in diastolic blood pressure 3, 9, 15, and 40 minutes after performing spinal anesthesia [P < 0.05]. The amount of ephedrine used in both groups did not show either any significant difference. Intrathecal bupivacaine may yield more hemodynamic stability than intrathecal lidocaine in elective cesarean section