prevalence of diabetic peripheral neuropathy and related factors

ABSTRACT

Diabetic peripheral neuropathy [DPN] accounts for 80% of diabetic foot ulceration; therefore neurologic examination plays a critical role in screening at risk patients. Our objective was assessment the prevalence of DPN and related factors based on clinical findings. This cross-sectional study was conducted on 124 diabetics who were randomly recruited from Diabetes Clinic of Dr. Shariati University Hospital [Tehran/Iran] in 2004. After gathering demographic data and blood sampling for fasting blood sugar [FBS], the questionnaires United Kingdom [UK], Michigan, Diabetic Neuropathy Score [DNS], and 10-g monofilament testing were administered. Analysis tests were chi-square, pearson correlation and logistic regression. The patient's age ranged 17-75 years; with 44% male. Ninety one percent suffered from type two diabetes and the mean duration of diabetes was 10 years. The mean FBS level was 181.5 mg/dl. While the prevalence of DPN based on Michigan, DNS, and monofilament testing was about 32-28%, some 54% were diagnosed by UK test. Tingling in the lower extremity was the most frequent complaint [42%]. The strongest linear correlation was reported between Michigan and DNS [r=0.7], and then between monofilament test and DNS [r=0.6]. The age >50 years, length of diabetes > 10 years, and FBS >200 mg/dl were the main risk factors for DPN based on DNS. It seems that the combination of Michigan and monofilament test can provide an accurate screening tool for detecting DPN. In addition, tight glucose control, regular assessment of the lower extremity, and to educate diabetics is urged in elderly diabetics, longer duration of diabetes, and those with high FBS