[HELLP syndrome: after delivery and favorable response to corticosteroid therapy: a case report in Bank Meli Iran hospital]

ABSTRACT

HELLP syndrome is a multisystem disease and a pregnancy complication consisting of Hemolysis, Elevated Liver enzyme level and low Platelet count. [1] We report on a patient with postpartum presentation. The patient was a 28 years old female at 30th wee, of her third pregnancy referred to bank melli hospital complaining of fever, chills, dysuria and frequency and admitted with diagnosis of urinary tract infection. After few days disease was progressed and abnormal laboratory tests ensued. Due to worsening general condition the pregnancy was terminated. After delivery platelet count decreased and she met all criteria of HELLP syndrome and received corticosteroid and the disease improved. Pathogenesis of HELLP syndrome is vague and there are different hypotheses all common in endothelial damage, vasospasm and coagulation system activation. This syndrome can present in the third trimester of pregnancy [%69] or after delivery [%31]. In most patient with post partum presentation, the disease is manifested during the first 48 hours after delivery. Corticosteroid therapy in all patient with complete HELLP syndrome [hemolysis, elevated liver enzyme level and low platelet count] is recommended. We reported on patient with complete HELLP syndrome presented post partum and good response to corticosteroid therapy