[Iodinated contrast induced acute renal and meningo-encephalitis]

ABSTRACT

The aim of this work is to report the cases of iatrogenic acute renal failure which has occurred after emergency realization of a cerebral scanner, with injection of iodinated contrast product at patients contracted by the meningoencephalitis. This prospective work was realized in a medical intensive care unit between January 2002 and December 2008. The criterion of principal judgment was the creatinin rate variations [>25% of its basic value] in the three weeks after a cerebral scanner with injection of iodinated contrast product at patients contracted by the meningoencephalitis. Eight patients were included among 360 meningoencephalitis cases corresponding to an incidence of 2.2%. The middle age was 43 +/- 17 years. The average time of appearance of the acute renal failure was 43 +/- 17 hours, with an average creatininemia of 66,8 +/- 37 mg/l. Three patients died. The incidence of this undesirable event remains weak but deserves a special attention. An adequate rehydration, before all using of the cerebral scanner with injection, should be realized for any patient presenting a meningoencephalitis