Serum calcium, phosphorus and protien changes in cancer patients undergoing abdominal surgery

ABSTRACT

To report the serum calcium, phosphorus and protein abnormalities in cancer subjects during abdominal surgery. 41 patients are collected [32 F/9 M] with a mean of age 57.78 +/- 12.7 years, who had undergone abdominal surgery. Serum samples were obtained on the day before surgery and on days 3 and 8 post surgery for measurement of serum total calcium, protein, and phosphorus. The different parameters studied fall significantly at day 3 and increase at day 8 postsurgery in all patients. The means levels of total calcium, phosphorus and protein before surgery are 2,04 +/- 0,2 mmol/l, 1,12 +/- 021 mmol/l and 55 +/- 7 g/l vs 1,9 +/- 0,26 mmol/l, 0,98 +/- 0,18 mmol/l and 50 +/- 8 g/l at day 3 post surgery. Post operative hypocalcemia was attributed to the fall in protein and the decrease in phosphorus may be resulted from renal losses of phosphorus due to extracellular volume expansion