In vitro antibacterial activity from marine algal extracts against virulent bacteria

ABSTRACT

In vitro screening using methanolic extracts of different marine algae and one sea grass showed antibacterial activity against eight virulent strains of fish and human pathogens II [VV] ratios of each methanolic extract were mutually added to give 21 interactions. The interaction between Udotea sp and Codium fragile extracts exhibited higher activities against Edwardsiella tarda [18 +/- 0.9mm] Vibrio ordalli [16 +/- 0.8mm] Klebsiella pneumonia [20 +/- 1mm] and Pseudomonas aeruginosa [16 +/- 0.8mm]. The bioactivity of this interaction was found to be more effective than that obtained from some common antibiotics including Lincolin, Streptomycin and Gentamycin. The chemical constituents of these two algal extracts and their interaction were characterized using thin layer chromatography and gas chromatographic - mass spectral analysis. The bioactivity of the separated compounds was estimated. Palmitic acid was the most active fatty acid