effect of propofol administration on the intraocular pressure

ABSTRACT

The use of propofol [2, 6, -diisoproylphenol] as an induction agent for general anaesthesia, has been reported to be smooth, without major adverse effects and associated with smooth recovery[1]. Previous studies have shown that its use is also associated with significant reduction in intraocular pressure [IOP][2]. In addition its use is beneficial in attenuating the rise in IOP assocaited with tracheal intubation. This study was undertaken to define the effects of propofol on IOP of normal and glucomatus eye when given as a single bolus dose of 2 mg Kg[1] intravenously followed by atracurium of intubation