Frequency of bone invasion and metastasis in round cell tumours of paediatric age groups

ABSTRACT

In this study a total of 14 patients of paediatric age group were included with round cell tumours of Retinoblastoma, Neuroblastoma, Ewings's sarcoma and Rhabdomyosarcoma. The frequency of metastatic involvement of the bone marrow was determined by aspiration and biopsy from posterior iliac crest. Routine investigations like haemoglobin, total leukocyte count and, platelets count were also carried out in all cases. Results show that the neuroblastoma was most common to metastasize to bone marrow. It was also noted that, aspirate and biopsy were found complementary in diagnosis of metastasis. However further work is needed to find out the frequency of metastatic involvement of bone marrow in a larger series of cases