Chemical and biological studies of Luffa aegyptiaca Mill. Seeds growing in Egypt

ABSTRACT

The crude expressed oil of Luffa aegyptiaca Mill seeds [18% w/w] [family Cucurbitaceae] was subjected to physical and chemical investigations. GC/MS analysis of the expressed oil revealed that it is built up mostly of linoleic [51.14%], palmitic [21.06%] and oleic [19.30%] acids beside lesser amounts of stearic [7.57%] myristic [0.70%] and eicosanic [0.23%] acids. Vitamin E was determined in the expressed oil by HPLC analysis and found to be 0.015%. In addition a mixture of free fatty acids; palmitic [58.89%] and stearic [41.11%] acids were isolated from the petroleum ether percolate. Identification of constituents was done through GLC analysis and comparing the relative retention time of peaks with those of authentic materials. The expressed oil showed significant anti-inflammatory, diuretic, and moderate progesterone like effects. The oil also exhibited antibacterial and antifungal activities