Estimation of potassium, calcium, and magnesium in blood and myocardial tissue, and diagnostic importance of urinary magnesium excretion in experimentally-induced myocardial injury

ABSTRACT

The results obtained in the present investigations point to a definite correlation between the onset of myocardial injury, electrocardiographic changes and biochemical changes. Changes in the electrocardiogram and elevated serum levels were paralleled by an increased excretion of magnesium in urine as early as one hour. Serum calcium and serum potassium levels did not show any significant result, but in coming days these ions including serum magnesium might help clinicians diagnose myocardial infarction. In this study, increased urinary magnesium excretion was found to coincide with elevated serum transaminases, and it is suggested that in addition to the other established diagnostic criteria, estimation of serum as well as urinary magnesium may be used as an additional index of myocardial infarction