effect of renal transplantation on uremic peripheral neuropathy

ABSTRACT

Six uremic patients were electrophysiologically assessed in regard to some of their peripheral nerves before and two times after they had undergone renal transplantation, in addition to eleven normal subjects as control. The latency, conduction velocity and amplitude of the compound sensory and motor action potential were tested for the ulnar and common peroneal nerves of unilateral limbs. The results of the tests done before the transplantation were similar to other studies showing mixed sensory and motor neuropathies of both axonal degeneration and demyelination types, while these results significantly improved two months after the transplantation, yet some of the parameters were still below normal ranges, and this improvement continued in the second assessment six months after surgery. These results indicate that successful renal transplatntation will improve the peripheral nerve function in those patients