[Effects of splenectomy on CBC changes in patients with ITP]

ABSTRACT

ITP is one of the most common cause of thrombocytopenia encountered in medical practice. The disorder has been estimated to affect approximately 1 in 10000 in the general population and to account for 0.18% of the hospital admissions. This study is performed to determine the response of the patients with ITP to splencetomy. This is a descrptive analytical cross-sectional study. The hospital files of 20 patients with ITP who were splenctomized in two university educational hospital were studied during 4 years. The samples were collected by census and one file was excluded because of its deficiency. The data were analyzed by using SPSS software. The mean ITP value was 30928 +/- 14352 SD during the two days before operation versus 476809 + 83252 SD during the two days after it [P=0.000]. The mean ITP value was 476809+83252 SD versus 381432+81265 SD during the two days after the operation and approximately one-year follow up, respectively [P=0.003]. According to our results, splenectomy is a suitable treatment for the patients with ITP. We suggest this procedure to all patients who are indicated in every age, because there is no correlation between its success and the patient's age, his response to previous medical treatments or diagnosis-splencetomy interval