Antimicrobial potency of three fruit drugs and formulated triphala drug against certain bacterial species associated with urinary tract infection [UTI] in vitro

ABSTRACT

Present paper deals with the findings of drug efficacy of three fruit drugs viz. Emblica officinalis. Terminalia belerica and Terminalia chebula extracted in aqueous, alcohol and ether - against four bacterial species commonly found associated with urinary tract infection [UTI] i.e. Escherichia coli, Klebsiella, Proteus and Pseudomonas species isolated from forty human urine samples. Maximum antimicrobial potency of each fruit drug was recorded for 100% concentrated extract in all the extract types [aqueous, alcoholic and ether] but a declined trend of drug potency was recorded with the dilution factor of the extract in all cases. In general, maximum drug efficacy was recorded in aqueous extract followed by alcoholic and ether extract. Similar trend was also found in the compound formulated drug [Triphala] prepared from above three different drugs. A positive correlation of drug efficacy with drug concentration was clearly found