Crohn's disease and idiopathic thrombocytopenic purpura in a patient with ectodermal dysplasia and immunodeficiency

ABSTRACT

In this case report we will describe a rare association between anhyrotic ectodermal dysplasia [AED] and immunodeficiency and autoimmunity [in our case Idiopathic Thrombocytopenic Purpura [ITP] and Crohn disease]. AED is a rare congenital disorder characterized by sparse hair, abnormal teeth and anhidrosis due to lack of eccrine glands. The survey of 87 cases with [AED] revealed only one Irritable Bowel Disease [IBD]. AED has only two relevancies with immunodeficiency [EDA-ID Ectodermal Dysplasia Anhyrotic with Immunodeficiency] and APE-CED [Autoimmune polyendocrinopathy, Candidiasis and Ectodermal Dysplasia] that in our case EDA-ID is strongly suspected