[ effects of hydro-alcoholic extracts of aerial components of Teucrium polium on pressure ulcer healing process and tensile strength in Wistar rats]

ABSTRACT

Wound healing represents a dynamic physiological process influenced by many factors. The aim of the present study was to evaluate the effects of hydro-alcoholic extracts of aerial components of Teucrium polium on the tensile strength in rat. Twelve Wistar rats were randomly divided into two equal [n= 6] treatment and control groups, pressure ulcer were made over the dorsal thoracic region according to the shyn model. Animals were treated with topical hydro-alcoholic extracts of aerial components of Teucrium polium twice a day post surgery until complete healing was achieved. Tensiometry were then studied. No significant difference in biomechanical parameters was observed among the ointment containing of extract 1%, vehicle and control groups. This study shows that topical application of Teucrium polium. Aerial components of Teucrium polium did not have any effect on healing of pressure ulcer in an animal model. Further studies are requiring for assessment of other extracts by different solvents of this plant on pressure ulcer wound healing