Effects of Allium sativum [Garlic] on systolic and diastolic blood pressure in patients with essential hypertension
Pakistan Journal of Pharmaceutical Sciences. 2013; 26 (5): 859-863
in English
| IMEMR
| ID: emr-138402
ABSTRACT
The present study evaluated the effects of garlic on blood pressure in patients with essential hypertension Patients [n=210] with stage 1 essential hypertension were divided into 7 groups named as A, B, C, D, E, F and G. Each group comprised of 30 patients. Each patient in group A, B, C, D and E has received garlic tablets at the dose of 300/mg. 600/mg, 900/mg, 1200/mg and 1500/mg in divided doses per day respectively for 24 weeks while Group F and group G were given tablet atenolol and placebo respectively. Blood pressure readings were recorded at weeks 0, 12 and 24. Present study showed significant decrease in both Systolic and Diastolic blood pressure in both dose and duration dependent manner. In each garlic treated group, significant reduction in SBP and DBP [p<0.005] were observed when compared with atenolol [P<0.005] and placebo
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Plants, Medicinal
/
Systole
/
Time Factors
/
Blood Pressure
/
Plant Extracts
/
Single-Blind Method
/
Analysis of Variance
/
Multicenter Studies as Topic
/
Treatment Outcome
/
Hypertension
Type of study:
Controlled clinical trial
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Pak. J. Pharm. Sci.
Year:
2013
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