antagonistic role of cinnamon on a destructive effect of alloxan on the rat testis a histological study

ABSTRACT

Diabetes mellitus is a chronic metabolic disorder characterized by a high blood glucose concentration [hyperglycemia] which is due to insulin deficiency and / or insulin resistance. As a consequence of the metabolic derangements various complications develop, so the aim of this investigation is to study [histological] the role of cinnamon - oil on the testis tissue of alloxan -induced diabetes rat. Forty -six male rats were used and divided into 3 groups group 1,6= animal control. group II, 20 = treated with alloxan and the 3[rd] group, 20 = treated with alloxan + cinnamon. Testis of group I revealed normal distribution of seminiferous tubules and spermatozoa filled the lumen of these tubules. Group II showed reduction in number of seminiferous tubules, and absence of spermatozoa in their lumen, besides the significant decrease in testis weight. Group III elicited retrained these changes to approximately its normal view. This herbs [cinnamon] decrease or protect the destructive effect of alloxan on testis tissue