Charge association with schizencephaly in a newborn infant: a case report

ABSTRACT

CHARGE association is an increasingly recognized non-random clustering of congenital malformations. We present a baby with readily recognizable clinical features that lead to a prompt diagnosis of CHARGE association. The baby also had a schizencephaly which makes us ponder that this could very well be a neural crest migratory disorder stressing the need for an expanded classification of [neurocrestopathies]. The recently recommended diagnostic criteria of CHARGE association are also reviewed