Oral ivermectin as a therapeutic agent in patients with scabies

ABSTRACT

To evaluate oral Ivermectin as a therapeutic agent to ordinary scabies. Random sample of 50 cases of ordinary scabies were treated with two oral doses of Ivermectin, 200 micro g/kg one week apart. The effect of drug was monitored clinically, by complete blood count, and confirmed parasitologically at the time of clinical presentation and at week4 of starting treatment. ELISA and Immunobloting using Sarcoptes scabiei crude mite extract was used to determine the levels of specific IgG and IgE in patients sera in comparison with 50 controls. The reported cure rate was 100%. However, 8% of cases presented with persistent itching, accompanying eosionophilia and high IgE levels. Ivermectin proved to be effective and promising drug for treatment of ordinary scabies