Genital ulcer development in patients with acute promyelocytic leukaemia treated with all-trans retinoic acid: a case series
Oman Medical Journal. 2013; 28 (3): 207-209
in English
| IMEMR
| ID: emr-140361
ABSTRACT
We report here four cases of genital ulcers that developed after the administration of all-trans retinoic acid [ATRA] for the treatment of acute promyelocytic leukemia [APL]. Between October 2007 and March 2010, three males and one female [age range 19-35 years] were identified to have genital ulcers after being prescribed all-trans retinoic acid [ATRA] as a part of chemotherapy for APL. This is the first series of cases describing genital ulcers, as a unique and rare complication of ATRA used for treatment of APL in these patients, with no other cause identified. Following temporary cessation of ATRA for a few days in these three cases, improvement of the ulcers was noted
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Scrotum
/
Tretinoin
/
Ulcer
/
Leukemia, Promyelocytic, Acute
/
Fever
/
Genital Diseases, Male
Type of study:
Case report
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Oman Med. J.
Year:
2013
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