spectrum of glomerular diseases on renal biopsy: data from a single tertiary center in Oman

ABSTRACT

To study the pattern of glomerular disease [GD] from the result of renal biopsies at our center. We conducted a retrospective review of 190 adult native renal biopsy reports from the pathology registry of renal biopsy performed at our hospital between 1992 and 2010. Lupus nephritis was the most common pathology 48/133 [36.1%] with a female preponderance. The most common primary glomerular disease was focal segmental glomerulosclerosis [FSGS] 26/133[19.5%], followed by membranous glomerulopathy [MGN] 13/133 [9.8%], and mesangial proliferative glomerulonephritis 6/133 [4.5%]. IgA nephropathy and acute proliferative glomerulonephritis each accounted for 4/133 [3.0%]. Membranoproliferative glomerulonephritis accounted for 3/133 [2.3%]. Focal proliferative and cresentic glomerulonephritis each accounted for 2/133 [1.5%]. Vasculitis was not common and there was no report of anti-GBM disease. Among the secondary glomerular diseases, lupus nephritis was the commonest condition with a female preponderance. Among the primary glomerular diseases, FSGS was the commonest. These results are consistent with global trend. IgA nephropathy is not common as the case in the Caucasian population. Vasculitis was not common and there was no report of anti-GBM disease