[Evaluation of osteoprotegrin concentration in the saliva of patients with generalized moderate chronic periodontitis]
Journal of Mashhad Dental School. 2013; 36 (4): 279-284
in Persian
| IMEMR
| ID: emr-140470
ABSTRACT
Periodontal disease is a chronic bacterial infection that affects the tissues supporting the teeth. Our effort in improving periodontal disease is to reduce destructive mediators. One of the Biomarkers is osteoprotegrin [OPG]. OPG is a protein which prevents osteoclast activity. The aim of this study was evaluationof osteoprotegrin [OPG] concentration in saliva of patients with generalized moderate chronic periodontitis and comparing it with that of healthy individuals. This study was carried out on 30 patients [15 patients with chronic periodontitis and 15 patients as the control group] referred to Ahvaz Jundishapour dental school. Saliva samples were collected and examined by ELISA. The data were analyzed by t-test. Mean OPG concentration in patients and control group were 117.63 +/- 84.13 mg/dl and 210.81 +/- 170.69 mg/dl respectively. The difference was not significant. It appears that OPG concentration in saliva cannot be used as a marker for the assessment of periodontal disease
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Saliva
/
Enzyme-Linked Immunosorbent Assay
/
Chronic Periodontitis
Type of study:
Controlled clinical trial
Limits:
Humans
Language:
Persian
Journal:
J. Mashhad Dent. Sch.
Year:
2013
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