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Male infertility and its association with metabolic syndrome and hypogonadism
Gulf Medical University: Proceedings. 2011; (29-30): 19-23
in English | IMEMR | ID: emr-140757
ABSTRACT
Hormonal profile alteration is seen in men with metabolic syndrome. Obese men have elevated levels of estrone and estradiol and there is also an attenuation of the pulse amplitude of luteinizing hormone [LH] which leads to a reduction of testicular production of testosterone. This study was conducted to assess the sperm morphology, prevalence of metabolic syndrome and association between gonadal hormones and parameters of metabolic syndrome among men diagnosed with infertility. Out of 434 men referred to the laboratory of Gulf Medical College Hospital and Research Centre, Ajman, UAE, 184 were diagnosed as infertile based on seminal parameters. Prevalence of metabolic syndrome and gonadal hormonal level among these infertile men were also studied. Data were analyzed with PASW 18 software and student t-test used for the significance. Mean age of the men referred for seminal analysis was 33 +/- 7.2 years. Forty two percent of the men were found to be infertile based on seminal parameters. Majority had total forward progression abnormality followed by abnormalities of head, tail and neck. Prevalence of metabolic syndrome among these men was found to be 19%. FSH and LH levels were significantly lower and prolactin levels were significantly higher [p<0.01] in men with metabolic syndrome. Estradiol and total testosterone levels showed no difference. High prevalence of metabolic syndrome was found among men diagnosed with infertility. Significant hypogonadism was found associated with metabolic syndrome among these men
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Index: IMEMR (Eastern Mediterranean) Main subject: Spermatozoa / Retrospective Studies / Metabolic Syndrome / Gonadal Hormones / Hypogonadism Limits: Humans / Male Language: English Journal: Gulf Med. Univ.: Proc. Year: 2011

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Index: IMEMR (Eastern Mediterranean) Main subject: Spermatozoa / Retrospective Studies / Metabolic Syndrome / Gonadal Hormones / Hypogonadism Limits: Humans / Male Language: English Journal: Gulf Med. Univ.: Proc. Year: 2011