Obesity as an important risk factor for certain types of cancer

ABSTRACT

Cancer could be described as the uncontrolled and unrestricted growth of malignant cells in any place of the body. It is a multifactorial disease which either heredity or environmental factors [such as nutrition, physical inactivity, alcohol, obesity, exposure to sun, environmental pollutants, infections] chip in incidence of cancer. In recent years, several researchers have focused on obesity as a potent cancer risk factor. Scientific evidences have suggested that obesity has associated with increased risk for a plenty of different types of cancer. The evidences are the most consistent for endometrial cancer, breast cancer between the postmenopausal women, and renal cell cancer. More contradictory results have reported about the colorectal, prostate, and pancreatic cancer. Although numerous studies have done according to the obesity and cancer relation or joint, but The molecular mechanisms in which obesity could increase the risks of cancer, have been poorly understood