[Henoch Schonlein nephrites in children: clinical features and outcome: about 34 cases]

ABSTRACT

To describe epidemiological, clinical, histological aspects, treatment and outcome of Henoch-Sch"nlein nephrits in children. A retrospective study was conducted on medical data of 34 patients with Henoch-Sch"nlein nephritis From January 1, 1996 to December 31, 2010 in the Pediatric Department of Charles Nicolle Hospital. Nephritis occured in 68,7%. The average patient age was 7 years 2 months and sex ratio was 0,6. Microscopic hematuria was noted in 23,5%, moderate proteinuria with or without hematuria was observed in 20,5%. Nephrotic syndrome was noted in 29,5%; nephritic syndrome was associated to nephritic syndrome in 23,5%. Isolated hypertension was noted in one patient. Follow-up was 2 years 6 months. Remission was noted in 26 cases [76,4%], minor urinary abnormalities in 7 cases [20,5%] and renal active disease in one case. Relapse was observed in 6 cases. Our study was characterized by the predominance of severe renal manifestations and low grade histological aspects as well as favourable outcome in most 90% of cases