Glycemic control in type 2 diabetes mellitus and its association with duration of diabetes and glycosylated hemoglobin A1

ABSTRACT

The aim of present study was to evaluate glycemic control in type 2 diabetes mellitus [DM] subjects and its association with the duration of diabetes and glycosylated Hemoglobin A1 [HbA1c]. A descriptive study, comprising of 571 diagnosed cases of type 2 DM were studied at the Diabetic clinic of Isra University/ consultant private clinics over a year period. Diabetic subjects were divided as; controlled diabetics [Group I. HbA1c 7%]. The data was recorded on a proforma. Blood glucose was measured by glucose oxidase method and HbA1c on automated clinical chemistry analyzer. The student`s t-test and chi-square were used for the quantitative and qualitative data respectively. Spearman`s correlations was used for a linear correlation of HbA1c with the duration of DM and random blood sugar [RBS]. The data was analyzed on SPSS version 16.0 for windows. P-value at male to female ratio of 21 and 0.91 in both groups respectively. RBS was elevated in 169 [66%] and 211 [66.9%] in both groups respectively [p=0.74]. Poor glycemic control was observed in 315 [55.1%] of subjects. Of 571 T2DM, 256 [44.8%] were having HbA1c <7% [Group I.] and 315 [55.2%] HbA1c >/= 7% [Group II]. The HbA1c values as high as >/= 13.1% was noted in 73 [12.7%]. A highly significant difference was observed in HbA1c [p=0.0001] between groups. Significant correlation of HbA1c was found with duration of DM [r=0.65, p=0.0001] but not with the RBS [r=0.038, p=0.36] We report poor glycemic control as indicated by glycosylated Hb A in type 2 diabetics. Public campaigns be attempted on regular basis to make diabetics aware of glycemic control