Esculapio. 2013; 9 (1): 15-16
in English
| IMEMR
| ID: emr-143126
ABSTRACT
To document the impact of JAK2 mutation on hemoglobin [Hb] level in patients with IMF. Thirty five patients were studied out of which 19 were JAK2 positive and 16 were JAK2 negative. Sample collection technique was purposive non-probability sampling. Variations were observed among the studied JAK2 positive and JAK2 negative patients regarding hemoglobin level. In JAK2 positive and negative patients mean hemoglobin level was 10.6g/dl and 8.6g/dl respectively [p=0.29]. Due to the better hemoglobin level, patients with JAK2 mutation have less transfusion requirements and are partially protected against severe anemias compared to patients with no mutation.
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Blood Transfusion
/
Hemoglobins
/
Primary Myelofibrosis
/
Mutation
/
Myeloproliferative Disorders
Language:
English
Journal:
Esculapio
Year:
2013
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