Acquired haemoglobin H disease associated with myelodysplastic syndrome
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2008; 18 (12): 784-786
in English
| IMEMR
| ID: emr-143391
ABSTRACT
A 60-year-old male patient presented with jaundice. Initial investigations showed anemia, indirect hyperbilirubinemia, raised Lactic Dehydrogenase [LDH] and increased reticulocyte count suggestive of hemolysis. Considering hemolysis low MCV and basophilic stippling on peripheral film, hemoglobin electrophoresis was done that showed Haemoglobin H [15.5%] that in the absence of family history was thought to be acquired. After bone marrow examination, the final diagnosis was Myelodysplastic Syndrome [MDS], Refractory anemia with excess of blast [RAEB] associated with acquired Haemoglobin H [Hb H] disease
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Hemoglobin H
/
Alpha-Thalassemia
/
Hyperbilirubinemia
/
Anemia, Hemolytic
Type of study:
Case report
Limits:
Humans
/
Male
Language:
English
Journal:
J. Coll. Physicians Surg. Pak.
Year:
2008
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