Cytotoxic effects of essential oils and extracts of some mentha species on vero, Hela and Hep2 cell lines
Journal of Medicinal Plants. 2010; 9 (35): 88-92
in English
| IMEMR
| ID: emr-143733
ABSTRACT
Mentha species are widely used in traditional medicine mostly as anti-flatulence. Nowadays, their usage as flavor and preservative in food, cosmetic and pharmaceutical industries has been developed. Moreover, cytotoxic effects of some Mentha species have been reported. In this study, cytotoxic properties of Mentha piperita, M. spicata, M. aquatica, M. crispa, M. pulegium and M. longifolia have been investigated. Different concentrations of essential oils and total extracts of six Mentha species were tested by MTT assay against Vero, Hep2 and Hela cell lines. The results showed that all samples were toxic against Vero, Hela and Hep2 cell lines [IC[50] 28.1-166.2 micro g/ml]. All examined Mentha species extracts and essential oils have cytotoxic effects but some of them could be considered as potent toxic agents
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Vero Cells
/
Oils, Volatile
/
Plant Extracts
/
HeLa Cells
/
Cell Line
/
Cytotoxicity, Immunologic
/
Medicine, Traditional
Language:
English
Journal:
J. Med. Plants
Year:
2010
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