Novel influenza A [HINI] virus-induced hemophagocytosis: first case reported in Saudi Arabia
Annals of Saudi Medicine. 2012; 32 (1): 86-89
in English
| IMEMR
| ID: emr-143974
ABSTRACT
H1N1 is a novel subtype of the influenza A virus. Since its reemergence in 2008, it has been reported to cause a variety of illnesses ranging from mild flu-like symptoms to severe multiorgan failure. We report a case of a young immunocompetent man who presented with progressive shortness of breath and rapidly developed multiorgan dysfunction, including pancytopenia from H1N1 infection during the 2010-2011 influenza season. His H1N1 pneumonia caused severe acute respiratory distress syndrome, respiratory failure requiring mechanical ventilation, rhabdomyolysis, myocarditis, hepatitis, encephalitis, and renal failure. During the diagnostic workup, a bone marrow biopsy was performed, showing hemophagocytosis secondary to the H1N1 infection. Unfortunately the patient died despite aggressive measures. Published reports contain only a few records of H1N1-induced hemophagocytosis. This is the first case report from Saudi Arabia with H1N1-induced secondary hemophagocytosis. It also highlights the fact that the virus is still very virulent and will pose a major annual health risk along with the seasonal influenza for at least the next few years
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Influenza A virus
/
Lymphohistiocytosis, Hemophagocytic
/
Influenza A Virus, H1N1 Subtype
Type of study:
Case report
Limits:
Humans
/
Male
Language:
English
Journal:
Ann. Saudi Med.
Year:
2012
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