multicenter cytological survey for the earlier detection of cancer cervix in Egyptian females preliminary results of the Egyptian/IAEA/WHO project [6/004] brachytherapy for cancer cervix uteri in the developing countries

ABSTRACT

Early detection of precancerous and cancerous lesions of the cervix uteri, has reduced the mortality and altered favourably the outcome of the management of such conditions. In some developing countries carcinoma of the cervix [CCU] is highly prevalent. Late clinical stage presentation prevails, consequently low cure rates [< 20%] are obtained. Cytodiagnostic policies are either Nation-wide [low and high risk females] or limited to hospital patients [Gynaecology out patients; mainly high risk group]. The Egyptian/IAEA/WHO Brachyrherapy project [6/004], is a pilot exercise which.includes a limited hospital oriented cytodiagnosis service, to detect early cases of precancerous and cancerous epithelial changes. The system includes a reference cytodiagonesitc center Nuclear Medicine and Radiation Oncology Center Kasr El Einy "NEMROCK" as well as the Pathology Department, Cairo University. 17 cytology collection posts in the affiliated hospitals and 6 peripheral cytodiagnositcs labs in Teaching and General Hospilals.The present material represents a sample which remains to reach a total of 60-100, 000. However the analysis of the available cytology material of the project and that of Cairo University Hospilals, showed the following.A lotal of 6488 cases [2035 from the project's affiliated hospitals and 4453 cases from Cairo Universily Gynaecology Department. Cervical intraepithelial neoplasia [CIN I, II and Ill] was detected in 277 cases [4.2%]. The mean age was 37.3 years. Although risk factors are basicaly the same as in the Euro-American series, yet only some are of significance in Egyptians.probably owing to the prevailing value system and the socio-cultural affliation of the majority of the population